Wakil Menteri Pertahanan Amerika Serikat ialah orang nomor 2 di Departemen Pertahanan Amerika Serikat. Menurut situs resmi DepHan AS, WaMenHan memiliki otoritas
Daftar Wakil Menteri Pertahanan AS Sunting
| No. | Nama | Masa jabatan | Menjabat di bawah |
|---|---|---|---|
| 1 | Stephen Early | 1949 - 1950 | Harry Truman |
| 2 | Robert Abercrombie Lovett | 1950 - 1951 | Harry S. Truman |
| 3 | Roger M. Kyes | 1953–1954 | Dwight D. Eisenhower |
| 4 | Robert Bernard Anderson | 1954–1955 | Dwight Eisenhower |
| 5 | Donald Aubrey Quarles | 1955–1959 | Dwight David Eisenhower |
| 6 | Thomas S. Gates | 1959 | Dwight D. Eisenhower |
| 7 | James H. Douglas | 1959–1961 | Dwight D. Eisenhower |
| 8 | Roswell Gilpatric | 1961–1964 | John F. Kennedy, Lyndon B. Johnson |
| 9 | Cyrus Vance | 1964–1967 | Lyndon Baines Johnson |
| 10 | Paul Henry Nitze | 1967–1969 | Lyndon Johnson |
| 11 | David Packard | 1969–1971 | Richard Milhous Nixon |
| 12 | Bill Clements | 1971–1977 | Richard Nixon, Gerald Ford |
| 13 | Charles W. Duncan | 1977–1979 | Jimmy Carter |
| 14 | W. Graham Claytor, Jr. | 1979–1981 | Jimmy Carter |
| 15 | Frank Charles Carlucci | 1981–1983 | Ronald Reagan |
| 16 | W. Paul Thayer | 1983–1984 | Ronald Reagan |
| 17 | William Howard Taft IV | 1984–1989 | Ronald Wilson Reagan |
| 18 | Donald Jesse Atwood Jr. | 1989–1993 | George H. W. Bush |
| 19 | William James Perry | 1993–1994 | William Jefferson Clinton |
| 20 | John Mark Deutch | 1994–1995 | Bill Clinton |
| 21 | John P. White | 1995–1997 | Bill Clinton |
| 22 | John J. Hamre | 1997–2000 | Bill Clinton |
| 23 | Rudolph F. de Leon | 2000–2001 | Bill Clinton |
| 24 | Paul Wolfowitz | 2001–2005 | George W. Bush |
| 25 | Gordon R. England | 2005–2009 | George W. Bush |
| 26 | William J. Lynn III | 2009-2011 | Barack Obama |
| 27 | Ashton B. Carter | 2011-2013 | Barack Obama |
| 28 | Christine Fox | 2013-2014 | Barack Obama |