Region adalah wilayah administratif tingkat satu di Guinea-Bissau.
| No. | Nama | Ibu kota | Kode | Luas (km²) | Populasi (sensus) |
|---|---|---|---|---|---|
| 1 | Bafatá | Bafatá | GW-BA | 5,981 | 210,007 |
| 2 | Biombo | Quinhámel | GW-BM | 839 | 97,120 |
| 3 | Bissau | Bissau | GW-BS | 78 | 387,909 |
| 4 | Bolama | Bolama | GW-BL | 2,624 | 34,563 |
| 5 | Cacheu | Cacheu | GW-CA | 5,175 | 192,508 |
| 6 | Gabu | Gabu | GW-GA | 9,150 | 215,530 |
| 7 | Oio | Farim | GW-OI | 5,403 | 224,644 |
| 8 | Quinara | Buba | GW-QU | 3,138 | 63,610 |
| 9 | Tombali | Catió | GW-TO | 3,377 | 94,939 |